Searchable abstracts of presentations at key conferences in endocrinology

ea0041oc8.3 | Thyroid - Translational | ECE2016

Identification of novel genetic loci associated with thyroid function

Brdar Dubravka , Boljat Antonela , Torlak Vesela , Punda Ante , Boraska Vesna , Gunjaca Ivana , Vidan Nikolina , Lozic Bernarda , Polasek Ozren , Hayward Caroline , Barbalic Maja , Zemunik Tatijana

Objective: Thyroid hormones have essential role in regulation of cellular growth, development and metabolism. Although genetic variants seem to be an important determinant of thyroid hormone levels the data about involved genes are still limited. Therefore, in order to determine genetic variants underlying thyroid-stimulating hormone (TSH), free thyroxine (fT4) and free triiodothyronine (fT3) plasma level we performed a genome wide association study (GWAS) in Croatian subjects...